Famed NBC personality Savannah Guthrie was spending time with her family before jetting off to Italy to work a Winter Olympic Games gig when she got the heartbreaking call that her mother was missing, according to a report.

The “Today” co-host was set to fly out Monday to Milan after hanging out with her husband and two kids over the weekend, CNN reported – but instead rushed to Arizona as authorities scrambled to find Nancy, 84, who was reported missing Sunday.

It was “the worst phone call of her life,” an NBC producer who knows Savannah personally told the outlet.

Savannah and Nancy Guthrie
Nancy Guthrie has been known to appear on her famous daughter’s show.savannahguthrie/Instagram
Investigators have said the beloved grandmother was taken from her home in the middle of the night in a possible kidnapping.

After Savannah received a call from family about her mother’s disappearance, she quickly flew out to Tucson, a source familiar with the matter told CNN.

Pima County Sheriff Chris Nanos said Monday on NewsNation that investigators and Savannah are in contact and police are working with her security team.

It’s unclear if Nancy was targeted because of her daughter’s high-profile.

Savannah Guthrie and Hoda Kotb on Wednesday, January 10, 2025.
Savannah Guthrie, seen here with former “Today” co-host Hoda Kotb, has been a fixture on NBC News in 1998.Nathan Congleton/NBC via Getty Images
“We’re not going to rule it out, but nothing’s pointing to her being targeted at this moment,” he said on NewsNation.

At a press conference Tuesday, Nanos said cops have little information on Nancy’s whereabouts or possible suspects. He has previously said that the octogenarian relies on daily life-saving medication, and that “if she doesn’t have it in 24 hours, it could be fatal.”

Here’s the latest on Savannah Guthrie’s missing mom

Nancy was dropped off at her home by family Saturday night, but when she didn’t make it to church Sunday morning, loved ones swung by the house.

When they couldn’t find her, they called 911 to report her missing.

Nancy Guthrie's house in Tucson, Arizona.
Nancy Guthrie went missing from her home in Tucson, Arizona.Rebecca Noble for the NY Post
It’s unclear when she vanished, but Nancy’s pacemaker stopped syncing with her Apple devices early Sunday morning, according to Fox News, citing a law enforcement source.

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Both Savannah and Nancy haven’t been shy about their ties to the Grand Canyon State, including when the pair dined on air together at a well-known Mexican restaurant.

“It’s so wonderful. Just the air, the quality of life is laid back and gentle. I like to watch the Havalinas and eat my plants,” Nancy said during the segment about the state, where she moved in the 1970s