SAVANNAH Guthrie’s distraught sister has been spotted for the first time since their mother vanished in a suspected abduction on Sunday.

Annie Guthrie was seen with her husband, Tommaso Cioni, driving away from their Tucson, Arizona home on Tuesday as investigators continue their probe into Nancy Guthrie’s disappearance.

*PREMIUM-EXCLUSIVE* *CALL FOR PRICING BEFORE USAGE* Savannah Guthrie’s sister Annie and her husband Tommaso are seen for the first time since their mother Nancy’s disappearance

Savannah Guthrie’s sister Annie has been spotted driving away from her Tucson, Arizona, home with her husband Tommaso CioniCredit: BackGridNINTCHDBPICT001056224396

Savannah and Annie are said to be assisting with the search for their missing 84-year-old mom NancyCredit: Facebook/Savannah Guthrie

*EXCLUSIVE* Law enforcement leave Savannah Guthrie’s sister Annie's Tucson home after a TWO-HOUR meeting

Federal and local law enforcement left Annie’s home on Tuesday following a two hour meetingCredit: BackGrid

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Annie lives in Tucson near her momCredit: Facebook/Annie Guthrie
Annie covered her face with a hood and sunglasses and Cioni, who was the last person to see Nancy, was also seen in sunglasses with his hand covering his face as they left the $650,000 property.

The sighting came as law enforcement from the FBI and the local sheriff’s office were also seen leaving the couple’s home following a two-hour meeting.

Annie and Savannah, who was believed to also have been at the meeting, are assisting with the search for their mom, who detectives believe was taken from her bed early Sunday morning.

The family has suffered through frustrating days of insignificant updates, with Pima County Sheriff Chris Nanos admitting on Tuesday that his department is completely stumped.

What we know about Nancy Guthrie’s disappearance…

Today host Savannah Guthrie’s mom is missing and cops fear she was abducted from her home in Arizona
Investigators have admitted they have no suspects, and said “we’re stumped” as they begged for tips
Savannah’s sister Annie, who was the last person to see Nancy, was spotted for the first time since her mom’s disappearance
Disturbing pictures have captured a trail of blood outside Nancy’s home, where signs of forced entry were also reportedly found
Several newsrooms have reported receiving what appear to be ransom notes, and detectives are looking into them
Today executives are said to be beefing up security at offices in New York City out of an abundance of caution
Savannah’s costar and friend Jenna Bush Hager announced she’s holding a prayer vigil in New York City for Nancy
Authorities have continued to desperately call for tips from anyone who was in the quiet neighborhood between Nancy being dropped off after dinner on Saturday night and missing church on Sunday morning.

Nanos clarified the timeline, saying that Nancy enjoyed dinner with Annie’s family – then was driven home by Cioni at 9:45 pm, who made sure his mother-in-law got inside safely.